Master Ge is the old class leader of the driver class, suffering from hyperthyroidism for more than a year, his condition is stable and controlled. Recently returned home from a business trip, his partner prepared some good food, and a bottle of Lao Bai Gan was placed on the table. Master Ge opened his belly and ate and sang. After waking up with a full stomach, Master Ge suddenly felt weakness in his legs and arms, and could not get up. At first, I thought I was too tired to go on a business trip, but I didn’t want to be sent to the hospital by my partner. Master Ge did not understand how, good food and drink, how will the weakness of the arms and legs? The doctor in charge explained the reason for this to Mr. Ge. The first thing you need to do is to get a good idea of what you are getting into. It usually occurs after overexertion, excessive alcohol consumption or overeating. Why does periodic paralysis occur after overeating? This is because after overeating, a large amount of glucose in the serum is transferred to the liver and muscles to synthesize hepatic glycogen and myoglycogen. Due to the need for anabolic synthesis, a large amount of potassium ions in the serum also enters the liver and muscle tissue along with glucose, causing the blood potassium concentration to drop. A normal blood potassium concentration is an important factor in maintaining normal muscle membrane potential and muscle excitability. Once the blood potassium concentration falls below normal, muscle excitability decreases and does not respond to stimuli, resulting in a paralyzed state. A small number of people with hyperthyroidism can have a slightly lower than normal blood potassium, and once they overeat or overexert themselves, the blood potassium will be further reduced, which may lead to periodic paralysis. This is exactly what happened to Master Ge, who came back from a business trip feeling tired, plus overeating and drinking, resulting in paralysis. The characteristics of hyperthyroidism periodic paralysis are: a history of hyperthyroidism or clinical manifestations of hyperthyroidism; acute onset, flaccid paralysis, characterized by heavy proximal, light distal, heavy lower extremities, light upper extremities, can also be limited to the lower extremities, facial muscles are not involved; serum T3, T4 is higher than normal, while serum potassium is lower than normal; electrocardiogram shows low potassium changes; generally after 5 to 12 hours to return to normal, individual heavy cases can last In some severe cases, it may last for several days, and potassium supplementation treatment can lead to rapid recovery of paralysis. The first step in the treatment of hyperthyroid periodic paralysis is immediate potassium supplementation, and in principle, oral potassium chloride is the mainstay if there is no vomiting. It should be noted that the most fundamental measure in the treatment of this disease is the treatment of hyperthyroidism, and with the effective control of hyperthyroidism, its attacks can be fundamentally relieved. In the rare cases where the attacks still occur, care should be taken to further determine whether there is periodic paralysis due to factors other than hyperthyroidism. In addition, it is important to avoid overexertion and overeating, and to eliminate triggers to help reduce attacks.