1. All patients must have a clear diagnosis before treatment, and generally there should be pathological or cytological diagnosis. Most anti-tumor drugs have certain toxicity, so they cannot be used as “diagnostic treatment” or placebo to avoid unnecessary losses to patients.
2. Patients need to be in good general condition with normal blood and liver and kidney functions to tolerate anti-tumor therapy. Drugs and doses should be carefully considered for those who have the following conditions.
(1) Old age and frailty.
(2) Previously received multiple courses of chemotherapy or (and) radiotherapy.
(3) Abnormal liver or kidney function.
(4) Significant anemia.
(5) leukopenia or (and) thrombocytopenia.
(6) Malnutrition.
(7) multiple bone metastases due to tumor.
(8) Adrenal insufficiency.
(9) Fever, infection or other complications.
(10) Cardiomyopathy.
(11) Allergic constitution.
(12) Esophagus or gastrointestinal tendency to perforate
(13) Patients with obvious cachexia should generally not use chemotherapy or biological therapy unless they are suffering from sensitive tumors and cannot tolerate the adverse effects of antineoplastic therapy.
(3) Only clinicians with certain specialist training should give patients anti-tumor drug therapy. Meanwhile. After determining the anti-tumor drug treatment, a specific plan should be made to choose the appropriate drug, combination, dose, route, method and course of treatment. Do not use the drugs for a long time or increase the dose blindly. During the treatment, we must closely observe whether there is allergy, gastrointestinal reaction, bone marrow suppression, liver and kidney function damage, etc. and give appropriate treatment. And give appropriate treatment.
4. The drug should be discontinued immediately and necessary measures should be taken when the following conditions occur in treatment.
(1) frequent vomiting affecting feeding or electrolyte balance.
(2) Diarrhea more than 5 times a day or bloody diarrhea.
(3) Any adverse reaction of degree 3 or higher.
(4) Myocardial injury.
(5) Toxic hepatitis.
(6) Toxic nephritis.
(7) Chemical pneumonia or pulmonary fibrosis.
(8) serious complications such as perforation, hemorrhage, embolism, and shock.
The course of treatment should be followed up at the end of the delivery period to observe the necessary long-term adverse effects.