In the STD clinic, there is a category of patients who make doctors feel very helpless, that is, STD phobia. These patients are partly cured STD patients; partly their sexual partners have or may have STDs, and they are worried about being infected; and partly they have heard of certain STD symptoms, and they themselves have taken them on board. Because the patient is firmly convinced that he suffers from one or more serious sexually transmitted diseases, which puts the doctor in a dilemma: say the patient does not have a sexually transmitted disease, then lose the patient’s trust; say the patient has a sexually transmitted disease, then aggravate the patient’s psychological burden. Clinical manifestations 1, psychological abnormalities: a high degree of fear of sexually transmitted diseases, suspecting that they have contracted sexually transmitted diseases, asking for confirmation. Attention to things related to sexually transmitted diseases is enhanced, and special attention is paid. They are particularly sensitive to minor physical discomfort and changes or even normal physiological phenomena, and believe that they are symptoms or early manifestations of sexually transmitted diseases. Compulsive reminiscence, and pester the doctor to repeat and emphasize their symptoms, the onset of the episode, raising questions, asking for explanations, and even manifested as compulsive exhaustion. However, the doctor’s explanation and have doubts or do not believe, or stubborn, resolute request for repeated examination and treatment. There are excessive fear, pain, worry, regret, anxiety and extreme mental tension. 2, behavioral abnormalities: mainly on the path of possible infectious diseases, high vigilance and avoidance, such as not dare to cohabit with their spouses, self-use of washing utensils, repeated forced washing, and some a day many times to seek medical advice to alleviate their mental stress. Patient complaints: (1) mental symptoms, such as dizziness, headache, insomnia, nightmares, palpitations, nausea, tinnitus, fatigue, bad breath. (2) vulvar symptoms, such as incomplete urination, or urethral itching, pain and discomfort, urethral orifice “secretion”, scrotum, lower abdominal pain and discomfort, and spermatorrhea, premature ejaculation, impotence, menstrual irregularities, decreased libido. Severe cases may feel the sensation of insect bites in the urethra or insect crawling in the vagina and other sensory allergy symptoms. (3) Non-specific symptoms, such as low back pain, lower limb weakness and soreness, skin itching and so on. (4) Signs: mainly manifestations of vegetative nerve function disorders, such as red face, excessive sweating, panic, fast heart rate, arrhythmia, and trembling of both hands. The above clinical manifestations disappear or are not obvious in work tension, attention shift, sleep, and there are no positive signs of venereal disease in systematic examination and skin-genital examination.