In the emergency department of a general hospital, we sometimes encounter patients who suddenly experience severe panic and palpitations, chest tightness and shortness of breath, and even a sense of near death. Patients usually think they are having a “heart attack”, but the doctor’s examination according to the heart disease protocol does not reveal any obvious abnormality, and it seems that the patient’s symptoms will be relieved on their own without giving the appropriate medication. At the same time, these patients are often skeptical of doctors telling them that there is nothing wrong with their heart and often or repeatedly go to the emergency room with severe heart disease symptoms. It is important to consider whether such patients are suffering from a “psychological disease”. This “psychosis” is clinically known as a panic attack. It is a manifestation of anxiety disorder, and its typical symptoms are sudden panic attacks and palpitations without any cause, as if the heart is about to jump out of the mouth, chest tightness and shortness of breath, as if unable to breathe and about to suffocate. There is also a strong sense of fear, as if one is about to die or lose one’s mind. Some patients may also experience hyperventilation, dizziness, numbness in the arms and legs, and gastrointestinal discomfort. These episodes are short-lived, usually lasting 5 to 20 minutes, and rarely last more than an hour before resolving on their own. Some patients seek emergency medical attention at the onset of an attack and their symptoms have resolved by the time they arrive at the hospital. Because there is no pattern to each seizure, seizures are often unpredictable and are not limited to a specific situation, but can occur anytime and anywhere. Most patients are always on the alert during the remission period and are often anxious about having another attack. They are also afraid of not getting help when they have an attack, so they actively avoid some activities, such as not wanting to go out alone, not wanting to go to crowded places, not wanting to travel by car, etc., or asking others to accompany them when they go out, which significantly impairs their social functioning. The causes of panic attacks are related to genetic factors, personality basis and psychological stress. The treatment of panic attacks includes both psychological and pharmacological measures and requires a longer treatment process. It should also be reminded that the phenomenon of panic attacks may be a single disorder and may also be a concomitant symptom of depression or other anxiety disorders, so when panic attacks occur, one should visit a psychiatric psychiatry department as soon as possible to seek professional help and treatment.