Vitamin B1 belongs to a kind of B vitamin, which has the effect of relieving fatigue, improving sleep, promoting digestion, nourishing nerves, etc. It also has a certain auxiliary effect on the prevention of beriberi. However, when supplementing vitamin B1, care should be taken to avoid combining with aspirin, aminophylline and other drugs. When taking vitamin B1, patients are advised to avoid the following six points: 1. Take on an empty stomach: Patients are advised to take vitamin B1 after meals or with meals, and the diversity of nutrients in the diet can promote the digestion, absorption and utilization of vitamin B1; 2. Take after drinking alcohol: When taking vitamin B1, it is recommended to avoid drinking large amounts of alcohol to Avoid the reaction of alcohol and other substances with vitamin B1, which may have adverse effects on the body; 3, combined with aspirin: vitamin B1 may cause a decrease in the pH of gastric juice, while aspirin will be hydrolyzed to salicylic acid in the stomach, both of which may simultaneously stimulate the gastric mucosa and produce other gastrointestinal disorders, so it is not recommended to take it at the same time; 4, combined with some proprietary Chinese medicines: some proprietary Chinese medicines, such as the Four Seasons tablets and The tannin contained in Shu Hemorrhoid Pills, etc. may combine with vitamin B1 and produce precipitation, affecting the absorption of both; 5. Combined with alkaline drugs: vitamin B1 is easily decomposed in alkaline environment, which may reduce the potency of vitamin B1 or even make it ineffective; 6. Combined with medicinal charcoal: vitamin B1 may be adsorbed by medicinal charcoal, thus reducing its effectiveness.