Gray hair is a very difficult disease to treat clinically, and its occurrence is often closely related to genetics, as well as some diseases and the patient’s emotions. In clinical practice, patients with gray hair do not experience significant improvement in the application of Chinese herbal medicine or proprietary Chinese medicine. Although herbs such as Chasteberry, Morinda citrifolia, and Radix Rehmanniae, Fructus Lycii, and Semen Cuscutae can be used for the oral treatment of gray hair. The reason is that gray hair is often related to liver and kidney deficiency when discussed carefully in the clinic. Therefore, it can be used for the treatment of gray hair, but it does not guarantee that it has a definite and effective therapeutic effect.