But to what extent is it appropriate to reduce hypertension, it needs to be considered according to different situations. Generally speaking, primary hypertension can be reduced to 140/90 mmHg; hypertension caused by diabetic nephropathy requires a reduction d to below 130/80 mmHg; in comparison, the most stringent requirement is caused by chronic kidney disease. In comparison, the most stringent requirement is the hypertension caused by chronic kidney disease, which is generally required to drop to 120/75mmHg or less. The reason why different causes of hypertension have different target values for lowering blood pressure is that the systemic damage caused by their underlying diseases is different, and hypertension as an aggravating factor, the aggravating damage is also different.