Barrett’s esophagus is a condition in which the original squamous epithelium of the esophagus is replaced by a proliferation of chemosis columnar epithelium and is a common and potentially serious consequence of chronic gastroesophageal reflux. The literature reports that endoscopy of patients with symptoms of reflux esophagitis reveals Barrett’s esophagus in 12% to 18% of patients. The risk of cancer in Barrett’s esophagus increases with the duration of reflux esophagitis symptoms, and Barrett’s esophagus and esophageal adenocarcinoma have shown a significant increase in Asian countries in the last decade or so. It is now believed that the risk of esophageal cancer in patients with Barrett’s esophagus is 30 to 125 times higher than that of the normal population, and thus is seen as a precancerous lesion. It is widely believed that Barrett’s esophagus evolves into adenocarcinoma through three stages: epithelial metaplasia – heterotypic changes – adenocarcinoma. It can be widely used in head, gynecological, cardiothoracic, renal surgery and endoscopic surgery, etc. The high energy of the system is excited and shot to the traumatic tissue for rapid coagulation and hemostasis, and the controlled and good hemostasis effect is the key to control bleeding without damaging the submucosal tissue as much as possible. The key to control bleeding without damaging submucosal tissues. Argon knife hemostasis is faster than ordinary electric knife, less damage to local tissues, bleeding patients can quickly stop bleeding, gastrointestinal polyps patients can be successfully coagulated, APC will transfer energy to the tissue to play the role of coagulation, not only for the treatment of gastrointestinal bleeding, but also for early cancer, benign and malignant stenosis, polyps, vascular malformation, Barrett’s esophagus, erosive hemorrhagic gastritis and other aspects of the treatment has a better effect And the action is fast, argon ion can reduce the temperature of bleeding wound, effectively reduce the consumption of oxygen and nitrogen around the tissue, reduce smoke, crust and tissue damage. Therefore, APC has the advantages of non-smoke, non-odor, safety and fast wound healing.