We have been carrying out laser treatment of esophageal varices for 9 years, and we have followed up its efficacy, and we have not seen a single case of recurrence in the reviewed cases, which indicates that its long-term efficacy is worthy of affirmation. The principle is that severe esophageal varicose veins are reduced in size by multiple ligation treatments and then laser treatment is performed. According to the mechanism of development of esophageal varices, pathological anatomy and practical observation, it can be concluded that most of the recurrence and bleeding sites of esophageal varices are located in the lower esophageal 5cm range. Therefore, the scope of laser treatment was also chosen in the 5cm range of the lower esophagus, and firstly, indocyanine green (ICG) was injected into the submucosal layer of the lower esophagus, whose function was to protect the submucosal tissues of the esophagus from the damage caused by the laser irradiation, and at the same time, to increase the efficacy of the laser treatment. The laser irradiation caused the lower esophageal mucosa to degenerate and whiten until the next part of the lower esophageal laser irradiation site appeared degenerative necrosis, scarring and hyperplasia repair. This eliminates the remaining varicose veins and prevents the formation of new varicose veins, thus achieving the goal of treating and preventing the recurrence of varicose veins.