Just as many families are running for joy to welcome the arrival of the dragon baby, there are some families who are looking forward to the arrival of the dragon baby, but they have a lot of worries. The year has been 31 Xiaowen, every month on time to report to the “aunt” has made her frustrated – the stomach has not moved. Four years ago, because and her husband are graduate students just graduated, “no car, no house”, for the time being do not want to “have a child”. An accident hit, she finally chose to give up. Now, have a car and a house, want to “have a child” but found it difficult to wish. To the hospital a check, Xiaowen realized that usually think “clean” of their own, even the fallopian tubes, cervix, pelvis have more serious inflammation, and this, it is the cause of her infertility. According to the results of a number of epidemiological surveys, in the cause of infertility, the female factor accounts for 40% -55%, and among them, the proportion of infertility due to reproductive tract infections for 20% to 60%. Inflammation, adhesion and obstruction of the reproductive tract caused by acute and chronic infections of the female reproductive tract are important causes of infertility. Inflammation of the channel makes it difficult for sperm to swim upstream The physiological characteristics and anatomical features of the female reproductive tract make it equipped with a defense function against external microorganisms. Under normal circumstances, due to the role of estrogen, the vaginal epithelium is thickened and rich in glycogen, which makes it more resistant to pathogens; and the presence of Lactobacillus, which makes the vagina can maintain a normal acidic environment (PH3.8-4.4), thus inhibiting the growth of other pathogens. The cervix, which is located between the vagina and the uterus, is itself in an anatomical position that is susceptible to injury and infection. However, under normal conditions, the presence of the tightly closed endocervical opening and the jelly-like mucus plugs formed by the secretion of the mucous membranes of the cervical canal act as mechanical barriers to prevent infection in the upper reproductive tract. However, once this natural defense is disrupted, changes in the endogenous flora or invasion by exogenous pathogens can lead to inflammation. Since pathogens deplete the glycogen in vaginal cells and change the pH of the vagina, they can affect sperm motility, block the upward mobility of sperm or cause sperm to agglutinate. Severe vaginal inflammation can also cause a large number of microorganisms and leukocyte hyperplasia, which reduces sperm vitality, decreases sperm survival time in the vagina, and even engulfs sperm; at the same time, the release of dead sperm and sperm antigens promotes the production of antisperm antibodies in the vagina, which in turn further affects sperm viability, motility, and penetration. If the cervix is also inflamed, the mucus properties are altered, again directly affecting the sperm upstream into the uterine cavity. As a result, the number of sperm entering the cervix and uterine cavity decreases, and conception rates are lower. Screening tools: Inflammation of the passageway is not difficult to detect and can be diagnosed by relevant secretion tests and pathogen culture. Inflammation in the uterine cavity makes it difficult for the embryo to survive The uterine cavity of a woman has the function of storing and transporting sperm, the conception of the egg to bed and the conception of the fetus. However, if the infection invades further, resulting in varying degrees of uterine adhesions, destroying the morphology of the uterine cavity and compromising the integrity of the endothelium, then even the sperm-egg union, implantation, and embryo development process will be difficult to survive due to the uterine cavity adhesion problem. Means of examination: Through hysteroscopy, the degree of inflammation in the uterine cavity can be clearly seen. Obstructed fallopian tubes make it difficult for sperm and eggs to meet In female infertility, blocked or incomplete fallopian tubes account for 1/3 of female infertility, which is a very important cause of infertility, and an important cause of blocked fallopian tubes is inflammation. Since the 1980s, the rapid spread of sexually transmitted infections, especially chlamydia, gonorrhea and other infections, resulting in an increase in tubalitis, tubal obstruction, tubal factors have clearly risen to the first place. Infertility caused by fallopian tube, on the one hand, mechanical obstruction directly leads to the obstruction of sperm-egg binding, as well as the obstacle of the transportation of fertilized eggs; on the other hand, cytokines produced by tubal inflammation and fluid accumulation will directly or indirectly affect the quality of sperms and eggs, and affect the formation of fertilization as well as the development of embryo, which ultimately leads to infertility. Means of examination: The severity of tubal pathology can be diagnosed by means of tubal fluids, uterine tubal iodine oil angiography and laparoscopy. Abortion, the culprit of gynecological inflammation Why does Xiaowen, who feels “clean”, suffer from inflammation? In fact, the infection leads to gynecological inflammation is not all life “unclean” caused, especially in China, abortion is the culprit. At present, China’s abortion number of large, young, repeat abortion. 2011 World Contraception Day, the latest survey results show that China’s annual average of more than 8 million cases of abortion, Beijing, Shanghai and other major cities, repeat abortion rate is as high as 50%, 88.2% of the infertile women have had an abortion. Even though there have been many advertisements for “minimally invasive abortion” in recent years, the trauma of abortion is not small at all. Repeated abortions, in particular, cause repeated damage to the uterine lining, making it thinner and affecting the environment for the fertilization of the egg. Multiple scraping of the uterus is also prone to pelvic inflammatory disease, subacute salpingitis, and secondary infertility. The shorter the interval between two abortions, the greater the harm. And if you choose an informal medical institution, the operation is not standardized, the instrument is not clean, these risks are even more incalculable. Can I get pregnant if I remove the inflammation? So, by removing the inflammation, is it possible to get pregnant again? Generally speaking, it is possible to regain pregnancy with timely and effective anti-infection treatment for inflammation of the external genitalia. However, it is important to note that bacteria and viruses infecting the vagina may spread upwards and cause intrauterine infections, which may vertically infect the fetus through the placenta and cause abnormalities, leading to miscarriage and premature labor. Therefore, it is important to treat the infection thoroughly and repeat the examination before pregnancy. Inflammation of the uterine cavity with mild to moderate lesions can be expected to be cured by hysteroscopic surgery and hormonal therapy, but the prognosis of some severe uterine adhesions is not good. For tubal obstruction, depending on the degree, it can be handled in different ways, such as water passages, surgery, etc. In the case of severe lesions, the option of assisted reproduction techniques may be needed to help with the fertility treatment. For more women, it is more important to avoid severe inflammation. In addition to avoiding abortion as much as possible, in the early stage of acute attacks of pelvic inflammatory diseases, timely, standardized and sufficient treatment should be provided to avoid its chronicity and sequelae.