Small particles on the lips may be related to contact labyrinthitis, sebaceous ectopic disorder and herpes of the mouth and lips. It is recommended that the patient go to the hospital for medical treatment to clarify the cause and then deal with it. 1. contact labyrinthitis: the patient’s mouth and lips are exposed to allergy-prone substances, such as mangoes and lip balms, which leads to lip inflammation due to allergy of the mucous membrane of the mouth and lips, manifesting as small particles on the lips, usually in large quantities, accompanied by itching, which require the removal of allergic factors and the use of anti-allergy drugs. 2. sebaceous ectopia: the patient’s lips have small particles, which may also It is caused by sebaceous gland ectopic disorder, which can be seen more clearly when the skin is tensed, and there is also a sense of fine particles when touched. Since sebaceous gland ectopia does not cause physical damage or cause other lesions, and most of them can subside on their own, so there is no need for special treatment; 3, oral lip herpes: is caused by the herpes simplex virus, the rash is a limited cluster of small blisters, like small particles, can be repeated, need to take oral antiviral drugs, external application of antiviral ointment for treatment. When small granules appear on the patient’s lips, frequent contact with the hands or even squeezing should not be used to avoid breakage and infection. If the number is found to increase, accompanied by itching, redness and swelling, patients are advised to visit the hospital in time to get a clear diagnosis and treat the cause.