Patients with mastocytosis can get pregnant normally. There is no necessary connection between mastocytosis and the ability to get pregnant. Mastocytosis is caused by high levels of estrogen in the body. 70%-80% of women of childbearing age suffer from mild mastocytosis. Patients with mastocytosis can ovulate normally, and a fertilized egg can be fertilized in the uterus. After the fertilized egg is laid, the levels of estrogen and progesterone in the pregnant woman’s body will change accordingly. Increased progesterone levels are more favorable for embryonic development. After delivery of the fetus, increased estrogen levels stimulate the development of the mammary glands, which produce milk to nurse the newborn. Pregnancy and breastfeeding have a protective effect on the mammary glands and can improve the symptoms of breast enlargement. However, breast enlargement can cause breast swelling and pain. Patients can treat it by regulating their mood, correcting bad habits, or using Chinese medicine under the guidance of a doctor. Unexplained breast swelling and pain should be promptly seen in the breast surgery department of a hospital to rule out mastitis, breast cancer and other diseases.