Barrett’s esophagus endoscopic treatment method I: 1. Principle: The principle is mainly to eliminate columnar epithelium and induce regenerative repair of squamous epithelium by various physical or chemical methods. Methods: Laser treatment: Currently, the more applied is Nd-YAG laser, which has a deeper tissue damage. The KTP laser is a green laser with a KTP crystal inserted into the 1064 nm infrared column of the Nd-YAG laser to produce a 532 nm laser. the KTP laser is very effective in eliminating superficial tissues, with little damage to deeper tissues. squamous epithelium can be regenerated quickly after KTP laser ablation treatment, but residual septic epithelium is also common and often requires Multiple treatments are often needed. 2.Multipolar electrocoagulation (MPEC): It is proved that MPEC combined with acid suppressant can reverse Barrett’s esophagus. 3, argon plasma coagulation (argon plasma coagulator, APC): APC is similar to MPEC, and is a new non-contact coagulation method, which can transmit high-frequency electrical energy to the surface of the target tissue through ionized argon gas to cause coagulation and denaturation; the treatment depth can be controlled at the mucosal layer of about 0.4 cm, therefore, complications such as bleeding and perforation The incidence of complications such as bleeding and perforation is low. However, after reviewing the relevant literature and performing statistical analysis, it was found that there was no difference in the treatment effect between APC and MPEC in the group.