Premature beats, i.e., preterm contractions, and their usual medications include beta-blockers, non-dihydropyridine calcium channel blockers, propafenone, amiodarone, etc., and they include atrial, junctional, and ventricular preterm contractions. 1. Atrial pre-systole: Usually no treatment is needed, when the symptoms are obvious or when supraventricular tachycardia is triggered by atrial pre-systole, treatment should be given, and therapeutic drugs include β-blockers (e.g., propranolol), non-dihydropyridine calcium channel blockers (e.g., diltiazem), propafenone, and amiodarone. 2. Junctional pre-systole: usually no treatment is needed. 3. Ventricular pre-systole: it is divided into two cases: organic heart disease and non-organic heart disease. (1) In the absence of organic heart disease, drugs such as beta-blockers (e.g., propranolol), non-dihydropyridine calcium channel blockers (e.g., diltiazem), and propafenone are preferred. Chinese patent medicines can also be used, such as Heart Stabilizing Granules, Ginseng Pine Nourishing Heart Capsules, and so on. (2) In principle, patients with organic heart disease should only deal with the disease of the heart itself and do not need to apply drugs for ventricular pre-systole. If obvious symptoms occur, beta-blockers (such as propranolol), non-dihydropyridine calcium channel blockers (such as diltiazem), amiodarone, etc. can be used. Patients with premature beats should standardize their treatment under the guidance of a doctor, and should not use medication on their own.