As the saying goes, a man can’t say “no” when he’s a man of the world. But on the contrary, many erectile dysfunction (ED) sufferers come to the clinic when a common phrase is, “I can not recently”. It is clear that “not working” is a common and intuitive way of saying ED, although it is not that accurate. According to the standard statement, in a considerable period of time (3 months), the male penis can not erect or erect but not firm, resulting in unsuccessful or discordant sexual life, which is the most important clinical manifestations of ED. At least three aspects should be included, one is the inability to achieve or maintain an erection sufficient for sex; second is the satisfaction of sexual life “can not”, now the erection can not let both sides to achieve satisfaction; third is the disease time should be at least 3 months, occasionally once or twice, a week or two weeks can not be counted. The above-mentioned “can’t” is the first thing we think, but also everyone will be concerned about. However, as we mentioned earlier, ED is not an independent disease, but a clinical syndrome associated with a variety of chronic diseases. Therefore, we can not only focus on the “lower body”, a “erection” blinders and not see the “Tarzan”, but also see the underlying chronic conditions that cause ED performance. Diabetes, coronary heart disease, atherosclerosis, hyperlipidemia and so on can lead to ED, we can not only see the erection problem, but also see the potential existence of the above, often easy to be ignored by us all chronic disease symptoms, precisely these problems lead to the occurrence of ED, development. If we ignore these manifestations, we will fall into the embarrassing situation of “treating the symptoms but not the root cause”, the so-called “headache, foot pain” is the case. On the contrary, we will be able to better grasp the situation of ED, a more comprehensive understanding of ED, reasonable and correct assessment of ED and lay a solid foundation for solving the problem. Of course, the “OK” can not rely on the subjective feelings and narratives of ED patients alone, the doctor will have some laboratory tests and instrumentation to help do objective analysis. Usually do some blood tests to understand the blood sugar, lipids, testosterone, etc., to understand the performance of any underlying chronic diseases; can also do color Doppler ultrasonography, to understand the local blood flow in the penis; other penile cavernosography, nocturnal penile erection monitoring and so on. Through these targeted modern examinations, we can get a more comprehensive understanding of those manifestations that are not detected by us.