Colorectal cancer (also known as colon cancer) is a common gastrointestinal malignancy that can occur in any part of the colon. It has a high incidence in North America and Western Europe, and colon cancer in the United States is the second leading cause of cancer death. In most provinces and cities in China, the mortality rate is the fifth to sixth of all malignant tumor mortality rates, and in recent years there is an increasing trend. Its incidence rate increases with age, starting from 40 years old and peaking from 60 to 75 years old. Colorectal cancer has obvious geographical distribution, and family hereditary factors have also been reported. Because of the slow growth rate of cancer tumors, a considerable amount of time passes before they reach the point of producing symptoms and signs. During the development of colorectal cancer surgery, especially the development of surgical instruments, such as anastomotic instruments and coagulation devices have made the surgical procedure simpler, faster, safer, and more effective. In addition, the concept of colorectal cancer surgery is also evolving clinical practice proves that standardized treatment of colorectal cancer after surgery can improve the 5-year survival rate of colorectal cancer by 6-8%. Among them, reasonable chemotherapy regimens, appropriate drug doses and adequate chemotherapy cycles are crucial, and also adjusting doses according to individualized differences and tolerability of patients, reducing adverse effects and avoiding under- and over-treatment are the core of standardization.