Severe retinopathy of prematurity (ROP) can lead to blindness if left untreated, but early and timely treatment can save most of them some useful vision. The younger the gestational age and the lighter the birth weight, the more likely retinopathy of prematurity is to occur. The purpose of fundus screening is to detect retinopathy of prematurity and to provide appropriate treatment in a timely manner. Fundus screening also allows for early detection of congenital abnormalities and other pathologies of the fundus. Currently, we use RETCAM for fundus screening with minimal pain and is safe, and our department has screened thousands of preterm infants without serious adverse effects. The first screening should generally be performed at 4-6 weeks postnatal or at 32 weeks corrected gestational age.