What is targeted therapy of tumor molecules?

In recent years, the incidence of tumor has been increasing year by year, the speed of knowledge update in the field of tumor treatment is amazing, and the progress of tumor drug research has greatly surpassed people’s expectation, providing hope for a large number of patients who are helpless by existing means in the clinic. Molecular targeted therapy for tumors is another major breakthrough in tumor treatment and has become another effective treatment after surgery, radiotherapy and chemotherapy. In clinical work, patients or family members often ask questions: what is targeted tumor therapy? What is molecularly targeted tumor therapy? Molecularly targeted therapy is to design the corresponding therapeutic drugs at the cellular molecular level to target the defined cancer-causing sites, which will only specifically combine with these cancer-causing sites after entering the body and cause the specific death of tumor cells without affecting the normal tissue cells around the tumor. Therefore, molecular targeted therapy is also called “biological missile”. What are the advantages of molecular targeted therapy for tumors? Targeted drugs are safe and well tolerated, so some of them can be used for a long time to control the growth of tumors, thus transforming the treatment of malignant tumors into a “chronic disease” similar to hypertension and diabetes, so that cancer patients can truly “face cancer openly, treat cancer scientifically, live with cancer and dance with cancer. This treatment method not only significantly prolongs the life of cancer patients, but also helps them to live with cancer. This treatment method not only prolongs the survival period of cancer patients, but also has less toxic side effects and effectively improves the quality of life of patients. Therefore, the miracle of transforming cancer into a chronic disease is becoming a reality. Are they available for all tumor patients? Since targeted drugs have so many advantages, can they be used by all tumor patients? Of course not, there are strict conditions for the use of molecular targeted therapy. It targets a specific target, just like a missile needs radar and satellite to help find and lock the target before launching, it also needs some specific examination means. Since patients have different conditions and different molecular biological status, the treatment plan varies and needs to be tailored and individualized after a thorough examination and evaluation. What are the commonly used molecular targeted drugs? In recent years, the application of molecular targeted drugs for tumor research has been hot, and some good results have been achieved, the following are commonly used in clinical practice: 1. It has greatly improved the efficacy of B-cell lymphoma, and Meroval combined with chemotherapy has been the standard regimen for B-cell lymphoma. Herceptin is used in breast cancer: it is a monoclonal antibody that targets the HER-2/neu proto-oncogene product and acts specifically on breast cancer cells that overexpress the HER-2 receptor. Combined with chemotherapy, it has significant efficacy in breast cancer. Gleevec: Gleevec is the first targeted drug used alone, and it is a milestone in molecular targeted therapy, which successfully blocks the internal connection of tumor cells. The use of Gleevec has given clinicians a new understanding of gastrointestinal malignant mesenchymal cell tumors. 4, ERSA: The targeted drug ERSA has created many miracles in the treatment of lung cancer: 2 years ago, a patient with advanced lung cancer, after surgery, radiotherapy and chemotherapy were ineffective, in a desperate situation, chose to apply ERSA treatment, after taking the drug for one month, the tumor miraculously subsided, and the patient could even travel abroad after continuing the drug; moreover, the side effects of this therapy were minimal, and the patient’s quality of life was improved while prolonging life. The patient was even able to travel abroad after the continuation of the drug.