If a child or adult has a strange appearance of protruding eyes, a sunken midface or a receding forehead, it may be Crouzon’s syndrome. This disease was reported and named by Frenchman Crouzon in 1912. It is a multifactorial deformity caused mainly by mutations in the fibroblast growth factor receptor gene. It is caused by premature ossification and closure of the bony suture around the pterygoid bone, resulting in impaired skeletal development of the skull and midface. The age of surgery for Crouzon syndrome should be considered according to the severity of the deformity and the suitable surgical method. 1, if there are serious eye protrusion, difficulties, cranial developmental deformity affecting brain development, early surgery should be performed around 2 years old; 2, if the deformity is serious, involving the cranial and mid-facial bones, the scope and risk of surgery can be considered. If the deformity is serious, involves the skull and the middle facial bones, the scope and risk of surgery, we can consider staged surgery; 3, those with less functional impact can be operated at a slightly older age, so that the child can have better tolerance for surgery. According to the situation of the child, there are mainly the following types of surgery: 1, frontal and mid-facial bone osteotomy whole block forward: applicable to the frontal and mid-facial cases are retracted. It is divided into two cases: (1) one is that the whole frontal and facial bones after osteotomy are directly moved forward to the appropriate position at one time and fixed; (2) the other case is that the tractor is placed after osteotomy and the tractor is used to move about 1 mm every day, and new bone will grow at the gap of osteotomy. After traction to the appropriate position, keep it for 6-8 weeks, and then remove the retractor after the new bone is fully ossified and solid. 2.Mid-facial bone osteotomy: It is suitable for the cases with simple mid-facial depression and normal frontal area. The nasal bone, orbital bone, maxilla, zygomatic bone, etc., which constitute the middle part of the face, are cut off and moved forward at the appropriate parts. Again, there are two ways to move forward in place at once and slowly with a retractor. In the past, due to the lack of perfect surgical techniques and the complex structure of the middle face, the surgeons had adopted a compromise surgical method, i.e., doing a lower position of the maxilla osteotomy, then doing a smaller forward shift, and then attaching the mandibular osteotomy to move back appropriately. This approach was very incomplete in correcting the deformity, and the nasal bridge and infraorbital area remained depressed after surgery and aggravated the narrowing of the oropharyngeal airway. Some surgeons nowadays also still use this method for technical reasons, which is inappropriate. The distraction osteogenesis technique for Crouzon’s syndrome is the most advanced and effective surgical method that is also less invasive and less risky. The surgical treatment of Crouzon syndrome is complex and requires a high level of skill on the part of the surgeon. Choosing the right hospital and doctor is an important thing. Third, the general diagnosis and treatment process: 1, comprehensive examination: through the clinical examination, X-ray and CT and other comprehensive examination, the initial diagnosis of Crouzon syndrome can be made. Usually the waiting time for bed is 2-3 days. Detailed preoperative preparation is performed after the hospitalization procedure. Including: clinical examination: the presence of cranial fissures, defects, meningeal-brain expansion; the presence of abnormal cranial morphology and specific performance formation; whether the orbital distance is normal, whether the visual acuity is normal; the presence of facial deformities and intellectual status. 2. Imaging examination: including X-ray photography and measurement analysis, CT and MRI, etc. 3.General condition examination: the patient’s liver, kidney, cardiopulmonary function and blood biochemistry and other related examinations to estimate whether the patient can tolerate a longer surgery under general anesthesia. 1500-2000mL of blood is prepared. 4.Model surgical design is performed according to X-ray measurement and 3D CT measurement. If the osteotomy anterior displacement style is used the patient should be informed before surgery that intermaxillary ligation may be required for 6-8 weeks after surgery, during which a liquid diet should be maintained in order to obtain good cooperation from the patient. Before surgery, the surgeon will communicate and discuss in detail with the patient and his parents about the patient’s current condition, the surgical approach, risks and potential complications, and obtain the consent of the child’s parents.