Patients with SLE should strengthen their own nursing care, which is also crucial to the prognosis of the disease. Patients should be made to maintain an optimistic attitude and good mood, and family members and friends should help them build up confidence to overcome the disease. Those with different manifestations of lupus erythematosus can be cared for accordingly (1) Pay attention to the prevention of colds and actively prevent and treat various infections. (2) Pay attention to the combination of work and rest and appropriate exercise. (3) Facial erythema: Keep the face clean, wash the face with water frequently, and wet compress the erythema with warm water of about 30℃. Avoid using alkaline soap, poor quality cosmetics, etc. (4) Mouth and nasal mucous membrane ulcers: maintain oral hygiene, clean your mouth after meals, and brush your teeth with a soft toothbrush. (5) Hair loss: Wash your hair with warm water and massage your scalp while washing. (6) Long-term bed rest: pay attention to prevent bed sores, turn more often, keep the area clean, pat the back to facilitate coughing up phlegm, and pay attention to changes in urine and stool. (7) Pay attention to the side effects of drugs: such as black stools, skin acne, hip pain, blurred vision, etc., should be reported to the doctor in charge and measures should be taken in a timely manner. (8) For patients with light allergy, it is better to wear a hat or hold an umbrella when going out in sunny weather to avoid the direct exposure to ultraviolet rays that may aggravate the disease. (9) Avoid the stimulating effect of chemical substances, and it is best not to use cosmetics. (10) Pay attention to quit smoking, quit drinking. Nicotine and other harmful ingredients in cigarettes can stimulate the blood vessel wall and aggravate the inflammation of blood vessels, should be quit. Alcohol is warm and strong, which can aggravate the internal heat symptoms of SLE patients and should not be consumed. Pay attention to recuperation and maintain a positive and optimistic attitude.