1.According to histopathology, more than 95% of colorectal cancers are adenocarcinoma, so this is the type commonly spoken of; 2.It is important whether it is early or late stage. In order to judge the severity of the patient’s condition, there is a unified standard (TNM staging system) to stage each first-time patient, which is roughly based on the size of the tumor, lymph node metastasis, and distal metastasis. Overall, the 5-year survival rate (temporarily understood as cure rate) for colorectal cancer patients is 65%. If the tumor is small and there are no lymph node metastasis and distant metastasis, then the situation is relatively good, but the opposite is more difficult. According to the data from the United States: if the tumor is confined to in situ (stage I), the 5-year survival rate is as high as 90.1%; if the tumor progresses to localization (stage II and III) but no distant metastasis occurs, the 5-year survival rate is as high as 71.2%; if the tumor has distant metastasis (stage IV), the 5-year survival rate is only 13.5%. 3. The same stage and the same type of diagnosis may have very different results among patients due to individual physical differences and different genetic mutations of tumor cells. Maybe you may be cured by the doctor’s systematic treatment, while the patient in the next bed is struggling hard. Different individual genotypes respond differently to drugs and the severity of side effects, and different oncogene mutation status also affects treatment. Of course, the overall physical condition of the patient is also very important. People who are alive and strong (as judged by ECOG PS score) will generally do better. 4. If you are in stage I, II or III, then the possibility of cure is very high. According to the 90.1% and 71.2% data, patients should be confident of a cure and be actively treated; if you are a stage IV patient, the median survival is 29 months, which means that if we rank the overall survival of 100 stage IV patients from shortest to longest, about the 50th patient will live for 29 months. I think this median survival can be simply interpreted as “average survival”, although it is not correct in terms of value and concept, but it is more consistent in terms of subjective feeling. 5. Even if the cancer is advanced, you still have a chance to be cured. Therefore, you should stay optimistic at all times and try your best to cooperate with the treatment and fight against the disease!