The best time of day for acupuncture depends on the patient’s specific situation and cannot be generalized. The time of day when acupuncture is recommended depends on the condition of the disease. According to the doctrine of ziwu-liu-in, in ancient times, 12 hours corresponded to 12 meridians, and acupuncture points could be taken according to different hours for better results, but this method of acupuncture at the corresponding time is not clinically applicable. At present, the time of acupuncture is usually chosen according to the actual situation of the patient, and acupuncture can be performed when the patient’s symptoms are most obvious, which is usually more effective. In addition, patients can also choose to perform acupuncture one hour after a meal according to their own schedule, when qi and blood are running more calmly, and can achieve the efficacy of disease prevention and treatment by supporting the righteousness and eliminating evil, nourishing the spleen and stomach, and helping yang to disperse cold. In addition, mid-day is the time when the essence is at its peak, so choosing 11-13 noon for acupuncture can also effectively enhance the body’s positive energy. Patients are advised to visit the acupuncture department of a regular hospital when they experience physical discomfort, so that an individualized treatment plan can be formulated by a professional doctor.