There are many types and dosage forms of antihypertensive drugs in clinical use, so the onset of action time is not consistent, and the way of taking them also affects the onset of action time. Commonly used antihypertensive drugs include beta-blockers, diuretics, calcium antagonists, angiotensin antagonists, and angiotensin-converting enzyme inhibitors. If you take betalactam extended-release tablets, which are beta-blockers, the onset of action generally starts 1-2 hours after oral administration; for nifedipine, a calcium antagonist, the onset of action is 30 minutes after oral administration. In addition, sublingual medications have an earlier onset of action than oral medications, and generally begin to take effect 15 minutes after sublingual administration. In addition, antihypertensive drugs are slowly lowering the patient’s blood pressure, so after taking antihypertensive drugs, if the blood pressure does not reach the standard, you should not take additional drugs or switch to other drugs to avoid low blood pressure, and should take the drugs correctly under the guidance of a cardiologist.