Isotretinoin is a basic medication for the treatment of acne, and it is also used as a medication for acne in the national treatment guidelines. 1. Fundamental control of acne mainly refers to the significant reduction of new acne, especially acne cysts. However, this does not mean that the disfiguring harm caused by acne will be fundamentally improved. For example, scarring. This needs to be addressed by other treatments. The first is the problem of teratogenicity. National treatment guidelines stipulate that pregnancy can only occur after 3 months of drug withdrawal, and we generally tell patients to stop taking the drug for 6 months before getting pregnant. Isotretinoin is a revolutionary medicine for acne and seborrheic dermatitis. When used well, it will give good results. Generally, comprehensive treatment is taken to reduce the disfigurement of acne.