Whether a breast cancer patient can have children is a more complex issue. If that patient tests negative for estrogen receptor (ER) and progesterone receptor (PR), that is, a patient who does not need endocrine therapy (if one or both of ER and PR test positive, the patient needs to receive endocrine therapy), we recommend that she should preferably not get pregnant within three years after the end of surgery and chemotherapy, because The incidence of tumor recurrence and metastasis is relatively high in the first three years. If after three years, the patient is in good health and has the need to have children, I think it is possible to get pregnant. For patients who receive endocrine therapy, the situation may be more complicated. Because this treatment requires continued medication for five or even ten years, these drugs may have some effect on the fetus, so it is advisable to use strict contraception while taking the drugs. But is it necessary not to get pregnant during the treatment? There is still a controversy. In patients who are hormone receptor positive and need to receive endocrine therapy, we do not encourage childbirth during treatment. However, assuming the patient has this need and the tumor is currently stable with no signs of recurrence and metastasis, if pregnancy is considered, the patient needs to carefully weigh the pros and cons. It is difficult to weigh the pros and cons from the doctor’s point of view because if you want to get pregnant, you have to stop the medication and interrupt the tumor treatment. If the tumor is okay while having the baby, it will be a perfect outcome; but the worst outcome may be that the baby is not saved and the tumor recurs or metastasizes at the same time. So this part of patients need to consider the risks involved carefully. For example, if the patient is 25 years old, she will only be 30 years old after 5 years of observation after treatment, and it is not too late to consider having a baby afterwards; however, if the patient is older and still has no child at the age of 35, she will be 40 years old after treatment, and the chance of pregnancy for women will drop dramatically at this time, so the patient needs to weigh the risks herself and decide whether to get pregnant or not. Some patients worry that they may stop menstruating or go through menopause after breast cancer treatment, and they worry that they cannot get pregnant without menstruation. Menopausal patients basically will not get pregnant again; menopausal patients have a lower chance of getting pregnant, but if ovarian function can be restored after menopause, then there is still a chance of getting pregnant again, but it may be difficult. It is important to emphasize that menstruation is not a requirement for pregnancy. Some patients can ovulate quietly and ovulate without changes in the endometrium (they may ovulate even if they do not have a period) and may happen to be able to conceive. Of course, without a menstrual cycle, the endometrium may not be fertile enough, and then the egg may not be able to successfully implant, leading to infertility or even miscarriage. This also reminds breast cancer patients from the other side that it is possible to get pregnant accidentally during post-operative treatment. Although menstruation may not resume at that time, there is a risk of pregnancy when ovarian function is restored, so good contraception is needed during treatment.