Modern medicine still lacks sufficient understanding of sleep disorders, and many explanations remain at the hypothesis stage. The definition of insomnia still remains in terms of subjective elements, and some scholars define insomnia as: “Clinically, it usually refers to the existence of a subjective dissatisfaction with sleep time and quality over a longer period of time, despite adequate sleep conditions and environment, and affects daytime social functioning experience. It includes difficulty falling asleep, disorders of continuous sleep maintenance, early awakening, and difficulty falling asleep after waking.” It also provides a careful classification of insomnia, which includes 10 subtypes: adaptive insomnia, psychogenic insomnia, heterogeneous insomnia, idiopathic insomnia, poor sleep hygiene, insomnia due to psychiatric disorders, insomnia due to drugs or substances, medically induced insomnia, unclassified insomnia, and physiologic insomnia. However, the excessive typing also reflects the complexity of the insomnia problem itself from one side. Obviously, it is difficult to have a clear description of insomnia from the perspective of pathological analysis in an anatomical sense, and the treatment lacks effective and lasting efficacy. Sleep disorders have been classified as “sleeplessness, nightmares and wandering spirits” in the literature of Chinese medicine for many generations, but mainly “sleeplessness” is the main cause. As for the process of sleep, TCM believes that it is a manifestation of “Yang entering Yin” and “Yang hiding”, and when the balance mechanism of Yin and Yang fails, sleeplessness will occur. The above theories have been widely and deeply discussed and practiced in “heart-kidney disjunction”. The heart and kidney are one of the main causes of sleeplessness. In the internal organs of the human body, the heart and kidney are a typical pair of “yin and yang”, and the heart in Chinese medicine is in charge of thinking and consciousness, so the positioning of the internal organs of sleeplessness and other problems lies mostly in the heart and kidney. The kidney is the water organ, and the heart is the fire organ, the kidney is yin and the heart is yang; in the eight trigrams of the I Ching, water is Kan, and fire is Li, the upper Li and the lower Kan form the Gua Zuiji, the meaning of the Gua is water and fire, “just soft and positive and position when also”, water up and fire down, that is, the heart and kidney intersection of self-consistent round state, the quality of sleep is relatively high, the nature of Yang is excited, up How can it descend? The nature of Yin is inhibited, down, and how can rise? According to the “lines” of the eight trigrams, the hexagram of Kan is a yang trapped in two yin, so there is a true yang in water, while the hexagram of Li is a yin trapped in two yang, so there is a true yin in fire, so that the problem of water and fire up and down. Although there are various clinical manifestations of heart-kidney disconnection, the most typical manifestation is sleep disorder, i.e. sleeplessness, which is also illustrated by the treatises of famous doctors in the past generations. The medical case of clinical evidence guide? Insomnia” said “The reason for insomnia, although not one, is always due to Yang not cross Yin.” Second, the theory of traffic heart and kidney treatment of sleeplessness traces back to the treatment of sleeplessness caused by non-intercourse of heart and kidney, which can be traced back to the treatment of heart and kidney yin deficiency and hyperactivity of yang in Zhang Zhongjing’s “Treatise on Typhoid”, “Shao Yin disease, which is more than two or three days, the heart is troubled and can not sleep, Huang Lian A Gou Tang is the main one.” In addition, Pig Fu Tang and Pig Skin Tang, which are used in the Treatise on Typhoid, for treating kidney deficiency that causes hyperactivity of heart fire, Ling Gui Gan Jujube Tang and Gui Zhi plus Gui Tang for treating heart deficiency and kidney water rushing upward, and Sour Jujube Soup, which is used in the Essentials of the Golden Horoscope for treating “false annoyance and sleeplessness”, these formulas aim at restoring the intercourse between heart and kidney, which are important inspirations for later generations of physicians to treat insomnia in which the heart and kidney do not intersect. These formulas aim at restoring the intercourse between the heart and kidneys, and are important inspirations for later medical practitioners in treating insomnia in which the heart and kidneys are not intercourse. In addition to the ones mentioned in Typhoid and Jin Kui, other prescriptions that have been used to treat insomnia by intercourse between the heart and kidneys include: 1) the Jiaotai Pill mentioned in Han’s Medical General, which consists of Huang Lian and Cinnamon in the ratio of 10:1; 2) the Sour Jujube Soup in Jing Yue Quan Shu; 3) the Up and Down Two Ji Dan in Zhi Zhi Lu; 4) the Tian Wang Tonic Heart Pill in Regimen Mi Jian; 5) the Zhu Zhu Zhu Pill in Yi Zhai Bai Yi Selective Formula; and 6) the Inner and Outer Injury Discernment and Confusion”; 6, Kong Sheng Pillow Zhong Dan in “Prepared Urgent Thousand Gold Essentials”, while the common drugs for the transportation of heart and kidney include Huang Lian, Cinnamon, Yuan Zhi, Lian Zi, Fu Ling (Shen), Bai Zi Ren, Wu Wei Zi, Sheng Di, etc. In addition, it is often said that the stomach is not harmonious then sleep restlessness, which explains the connection between digestive system problems and sleep, but what exactly is the mechanism of action in the middle, there are various explanations, and a number of people believe that the middle link is precisely the heart and kidney non-interaction. The “standard of evidence and treatment” said: “It is better to supplement the kidneys than the spleen, because the spleen is crossed with the heart and the kidneys. Taoist coitus heart and kidney, the spleen for the yellow woman, that is, this meaning.” The Danxi Xinfa says: “The spleen has the body of Kun Jing, but has the transportation of Qian Jian, so it can make the heart and lung Yang descend, the liver and kidney Yin rise, and become the Tai of the intersection of heaven and earth.” Zhang Yuqing said, “I do not know that water and fire do not help, not water and fire do not want to help, there is a way to block the intersection of water and fire also, the central pivot is also.” It is explained that the spleen and stomach are in harmony with each other, and they are the pivot of the heart and kidney traffic, so the insomnia caused by the spleen and stomach and the insomnia caused by the heart and kidney are seemingly different, but the essence is the same. The insomnia caused by the spleen and stomach seems to be different from the insomnia caused by the disconnection of the heart and kidney, but the essence is the same. The Book of Discernment? Sleeplessness” points out: “People have day and night can not sleep, the heart is very agitated, this heart and kidney do not cross. If you can’t sleep in the day, it is because the kidney does not hand over to the heart; if you can’t sleep at night, it is because the heart does not hand over to the kidney. This day and night all sleeplessness, is the heart and kidney two do not intersect ear. The reason why the heart and kidneys do not cross, the heart is too hot, and the kidneys are too cold. Heart originally belongs to the fire, too hot fire inflammation in the upper and can not be delivered to the kidney; kidney originally belongs to the water, too cold water sink in the lower and can not be delivered to the heart. Then the treatment, so that the heart of the hot is not hot, the kidney of the cold is not cold, the two lead to and from the two together.” It can be seen that the insomnia of the heart-kidney disjunction type should be further investigated whether it is mainly dominated by the heart or the kidney, and the pathological aspects should be distinguished whether the heart disease is not crossed with the kidney or the kidney disease is not crossed with the heart, or the spleen and stomach are unable to mediate between them, and focused countermeasures should be taken respectively. In addition to clinical insomnia, heart-kidney disjunction is often accompanied by other concurrent symptoms, such as palpitations, forgetfulness, dizziness and tinnitus, waist and knee weakness, dream loss, dry throat and dry mouth, constipation, abdominal distension, hot flashes and night sweats, red tongue and fine pulse, etc. It also helps us to determine the specific type of heart-kidney disjunction, which is inclined to kidney yin deficiency, often with symptoms such as tiredness, seminal emission, white turbidity and forgetfulness; inclined to excessive heart fire, often with restlessness, dry throat and dry mouth, red tongue If the heart fire is excessive, there are symptoms such as restlessness, dry throat and mouth, and red tongue; if the spleen and stomach are dysfunctional, there are symptoms such as constipation and abdominal distension. The heart and kidney are both important organs of the human body and play a very important role in maintaining life activities. The two organs do not exist in isolation, but cooperate with each other and have constraints, and there are many theories related to the heart and kidney in Chinese medicine. From the modern classification of diseases, the heart and kidney related diseases in TCM at least involve mental and emotional diseases, urinary system diseases, heart diseases and reproductive system diseases. In addition, diseases such as seminal emission, gonorrhea, impotence, nightmares, wandering spirit, bewilderment, sweating, blood in the urine, collapse, edema, palpitation, heart pain, and thirst are also more or less related to the physiology and pathology of heart-kidney related diseases such as heart-kidney non-intercourse and yin deficiency and fire, etc. Modern research has further expanded the spectrum of heart-kidney related diseases. Modern research has further expanded the spectrum of heart-kidney related diseases, such as senile dementia, menopausal syndrome, osteoporosis, heart failure, etc. have also been included, and many phenomena can also be explained from the perspective of heart-kidney non-intercourse. The analysis of medical cases of sleep disorders through the ages also helps us to further understand the heart-kidney related theories and guide the treatment of other connected diseases.