Spermatorrhea is one of the common infectious diseases in men, the onset of which is mostly between 20 and 40 years old, with hematospermia as the main clinical manifestation, divided into acute spermatorrhea and chronic spermatorrhea, with chronic spermatorrhea being more common. Acute vesiculitis is mostly caused by bacterial infection, which is accompanied by hematemesis, sometimes painful ejaculation, fever and chills, pain in the perineum, and pain radiating to the groin and testicles. Chronic vesiculitis can be secondary to chronic prostatitis and acute vesiculitis, with recurrent clinical hematospermia, which is difficult to heal. The infecting bacteria are E. coli, followed by staphylococcus, streptococcus and diphtheria-like bacilli. 1. choose antibiotics Acute seminal vesiculitis should be treated until the symptoms disappear completely, then continue the medication for 1 to 2 weeks; chronic seminal vesiculitis needs to continue the medication for more than 4 weeks to consolidate the efficacy. According to our experience, cephalosporins combined with quinolones are applied with good effect; the alternative drugs are roxithromycin and doxycycline. 2, Chinese medicine treatment Acute stage is common with damp-heat conjunctive evidence, commonly used gentian diarrhea liver soup. In the chronic stage, the evidence of yin deficiency and fire is common, and Zhi Bai Di Huang Wan combined with Er Zhi Wan is often used. 3, local treatment rectal administration suppositories such as wild chrysanthemum suppositories, prostate security suppositories, nano-silver antibacterial water gel, etc., such as the anus; or Chinese herbal enema treatment, according to the specific circumstances of the patient dialectical administration of drugs, once a night. 4, abstinence Avoid too much intercourse, let the prostate, vesicular gland rest, the first month is best to prohibit intercourse, the next 3 – 6 months, 1-2 times a month intercourse is appropriate, in order to reduce the degree of sexual organ congestion. 5, chronic vesiculitis, can be treated by rectal microwave therapy Can promote local blood circulation and inflammation absorption, especially for those with obvious pain symptoms. 6, hematosperm treatment can also be used ethylene estradiol 1 mg to strengthen the diazepam 5 mg orally, 3 times a day, for 2-3 weeks, can make the hematosperm stop.