Generally, H. pylori infection does not cause hives. Urticaria can be categorized into acute urticaria and chronic urticaria. Acute urticaria can be caused by fish and shrimp and other foods, viruses, furazolidone and other drugs and other factors; chronic urticaria can be associated with viruses and other infections, autoimmune, long-term stress and other psychoneurological factors, especially the longer course of the disease, the effect of conventional doses of antihistamine treatment is not good with autoimmune factors. The causes of urticaria can be divided into exogenous and endogenous. Exogenous physical stimuli such as friction, fish and other foods, penicillin and other drugs, strenuous exercise, etc.; endogenous can be chronic insidious infections, fatigue, mental stress, hypothyroidism and other autoimmune and chronic diseases. Helicobacter pylori infection can lead to chronic gastritis, gastric ulcer, duodenal ulcer and other diseases, generally does not cause urticaria.