One of the risk factors of coronary heart disease is high blood pressure, and coronary heart disease can in turn affect blood pressure and cause it to rise. Coronary artery disease affects blood pressure mainly because of the increased sympathetic excitability caused by coronary artery disease, which leads to faster heart rate and higher blood pressure. Patients with coronary artery disease commonly suffer from chest pain, irregular palpitations, shortness of breath and so on. Patients with coronary artery disease are often accompanied by increased sympathetic excitability, so basic drug therapy includes beta-blockers, which are used to inhibit sympathetic activity and thus improve symptoms and prognosis. beta-blockers can play a role in anti-myocardial ischemia and improve sympathetic excitability, and patients with coronary artery disease can develop a state of cardiac insufficiency that leads to fluid retention, which can also cause a secondary increase in blood pressure.