How long to take paroxetine for premature ejaculation will be better varies from person to person; some take half a month, some have no obvious effect. Paroxetine is a selective 5-hydroxytryptamine reuptake inhibitor, the main effect is to raise the ejaculation threshold, so that ejaculation is delayed, and then to achieve the role of the treatment of premature ejaculation. Specific therapeutic effects also need to vary from person to person, some patients in about half a month after taking the drug to see the effect, it is recommended to follow the doctor’s instructions to use; but when there are reproductive organ lesions, such as vas deferens blockage, tumor compression, the use of paroxetine has no obvious therapeutic effect. Adverse reactions such as dizziness and headache, diarrhea and abdominal pain, insomnia, loss of vision, blurred vision, tinnitus, nausea, loss of libido and other adverse reactions can occur after the use of paroxetine, and the drug should be stopped and observed in time. This drug also has some contraindications, such as allergy to the components of the product is contraindicated; severe depression is contraindicated; liver and kidney insufficiency is contraindicated. Premature ejaculation patients are advised to seek medical treatment in a timely manner and use the drug as prescribed by the doctor.