[Abstract] Objective To investigate the application value and safety of uterine artery embolization intervention for postpartum hemorrhage. Methods Uterine artery intervention was selected in 16 patients with different etiologies and bleeding volumes of postpartum hemorrhage. Conclusion Uterine artery embolization has the advantages of rapid hemostasis and few complications, and is a reliable treatment method for postpartum hemorrhage. Keywords: postpartum hemorrhage; intervention; fertility function; safety 1. Materials and methods Postpartum hemorrhage has always been one of the serious complications in obstetrics and delivery, and patients often suffer from shock due to excessive blood loss, which is even life-threatening. The results are reported as follows. 1.1 General data: 235 patients with postpartum hemorrhage were admitted to the Department of Obstetrics and Gynecology of our hospital from 2005 to 2012, with a postpartum hemorrhage rate of 1.67%. There were 9 cases of spontaneous delivery and 7 cases of cesarean delivery. There were 6 cases of anterior placenta, 5 cases of hypertensive disorders of pregnancy, 1 case of abnormal liver function and 4 other cases. The bleeding volume was between 1000 and 1500 mL in 12 cases, and the bleeding volume was more than 2000 mL in 4 cases. 1.2 Methods: While actively transfusing blood and fluids to maintain vital signs and resist shock, the patient was placed in a lying position with the right lower limb slightly abducted, and an arterial catheter was inserted through the right femoral artery under local anesthesia, and the internal iliac arteries on both sides were intubated and imaged separately. After the arterial catheter was withdrawn, the puncture site was compressed and bandaged for 24 h. After the operation, the puncture site was bedridden for 24 h. The circulation of the lower limbs and the bleeding of the puncture were observed. Postoperative correction of anemia and appropriate supportive and anti-infection treatment were continued and followed up after discharge. 2. Results 2.144 patients had stopped vaginal bleeding after intervention, 5 cases had significantly reduced vaginal bleeding, and only a small amount of bloody discharge. Postoperative infection prevention treatment, observation of vital signs, complications and symptomatic treatment were routinely performed. 2.2 Three patients had postoperative fever, which improved after symptomatic treatment. One day later, eight patients reported mild pain in the lower abdomen, which disappeared after 3 to 5 days without the use of dulcolax. 3, Discussion 3.1 The causes of postpartum hemorrhage include weak uterine contraction, placental factors, soft birth canal injury and coagulation dysfunction, the most common clinical cause is weak uterine contraction, 72% in this case, and the decision to intervene was made after routine strengthening of uterine contraction was ineffective. Postpartum hemorrhage is the leading cause of maternal death. The treatment of postpartum hemorrhage should be to preserve reproductive function as much as possible while saving life. In the past, all kinds of refractory postpartum hemorrhage often required hysterectomy, and although hysterectomy or total hysterectomy is effective in stopping hemorrhage, the loss of reproductive function after hysterectomy has serious adverse psychological effects on young women, and also affects ovarian endocrine function and women’s health. It is difficult for the patient to accept it ideologically. With the development of radiological interventional technology in recent years, vascular interventional therapy – transcatheter arterial embolization has become an increasingly effective method for treating postpartum hemorrhage, which can not only achieve rapid hemostasis and save lives, but also preserve the uterus and avoid physical and psychological trauma caused by hysterectomy. 3.2 The success rate of vascular intervention is high, reaching 100% in this case, with obvious results and minimal bleeding. The operation time is short, averaging 25 min in this case. a few people have a little fever and pain, 11 cases in this case, which can be relieved in a short time. Interventional treatment is less invasive, precise in hemostasis, safe and effective. Angiography through femoral artery puncture cannula can accurately understand the site of pelvic artery bleeding and bleeding situation, and embolize the bleeding vessel directly, thus reducing the blindness of diagnosis and treatment, and winning valuable time for rescuing patients. Therefore, interventional treatment for postpartum hemorrhage has the advantages of rapid, effective, less traumatic, faster recovery and fewer side effects, avoiding the damage and possible complications of open surgery, and has achieved positive efficacy in clinical practice. 3.3 It is worth noting that the blood supply to the ovary comes from the ovarian branch of the uterine artery and the ovarian artery, of which the former provides at least 50% of the blood supply, and excessive embolization of the uterine artery should be avoided to prevent accidental embolization of the ovarian branch of the uterine artery, which may affect ovarian function or even premature ovarian failure. Among the 49 patients who underwent the intervention in our hospital, 45 of them returned to normal menstruation at follow-up, 15 of them became pregnant again and 4 were lost to follow-up, with no intermediate or long-term complications. In conclusion, uterine artery embolization for patients with postpartum hemorrhage is worth promoting because of its rapid effect, precise hemostatic effect, low postoperative side effects, and preservation of reproductive function in women of childbearing age.