Diarrhea after taking Misoprostol is a normal phenomenon. Because Misoprostol has a contraction effect on the smooth muscle of the gastrointestinal tract, it can cause an increase in intestinal peristalsis, manifesting as nausea, vomiting, diarrhea and other symptoms. If the diarrhea symptoms are mild, no treatment is needed, you can drink more warm water, usually 1-2 hours can be relieved by itself. If the diarrhea is severe, accompanied by abdominal pain, falling, nausea, vomiting and other symptoms, it can be treated with oral montelukast, metoclopramide, probiotic tablets and other drugs under the guidance of a doctor. If patients develop complications such as dehydration, electrolyte disorders, acid-base imbalance, etc., they need to be treated with rehydration, stop the medication in time, go to the hospital and give intravenous rehydration according to medical advice to correct the water and electrolyte disorders. During the period of medication, attention should be paid to eating warm, soft and easily digestible food, such as millet porridge and noodles, etc. Do not eat spicy and stimulating food, avoid eating cold and raw food, and pay attention to keeping the abdomen warm to avoid getting cold. In addition, attention should be paid to the contraindications of Miso, namely, it is prohibited for those who are allergic to prostaglandins, glaucoma, asthma, allergic colitis and allergic constitution, those with cardiac, hepatic, renal or adrenal cortical insufficiency, and pregnant women.