Primary thrombocythemia is usually reviewed once a month, some patients need to be reviewed weekly in the first 2 months, and can be reviewed once every 3 months after stabilization, the specific review time is recommended to follow the doctor’s advice. Primary thrombocythemia is a chronic myeloproliferative disease, most patients will have bleeding symptoms, mainly gastrointestinal bleeding, but also gum bleeding, nosebleeds, hematuria and so on. Due to the increase in platelets, patients may also show signs of thrombosis in the arteries or veins. In addition, patients also commonly have symptoms of splenomegaly. Patients usually need to be rechecked once a month after treatment to observe the patient’s therapeutic effect. However, if the patient is using hydroxyurea as a chemotherapeutic drug, it is necessary to pay attention to check the blood routine once a week in the first 2 months of treatment, then once a month, and once every 3 months after the blood image is stabilized. Specific diagnosis and medication need to be under the guidance of a physician.