The early stage of breast cancer may be asymptomatic, and as the disease progresses, it may show local and systemic symptoms. 1.Lump: It is the first symptom of breast cancer. 2. Pain: Most breast cancer patients lack pain symptoms. Due to the less occurrence of pain, breast cancer is not easily detected at an early stage. Pain is often manifested as tingling, swelling or hidden pain in the breast, and periodic pain may occur if the cancer is accompanied by cystic hyperplasia in the breast. 3.Breast skin changes: Breast tissue is surrounded by superficial fascia located under the skin, and the deep and superficial fascia are connected by Cooper’s ligament. 4. Changes in the breast whorl 5. Changes in the nipple areola ① Nipple retraction and orientation changes: The nipple is flattened, retracted, sunken, and changed in orientation until it is completely retracted under the areola and the nipple cannot be seen. Nipple indentation due to breast cancer is different from congenital nipple invagination. The latter can often be pulled out by hand, while nipple retraction due to breast cancer cannot be pulled out, and lumps can be found under or around the sunken nipple ② Eczema-like changes of nipple: initially itching of nipple, thickening of nipple epithelium, desquamation, oozing, gradually appearing vesicles, vesicles and repeated crusting and chopping off, red flesh buds appear after the skin of areola peels off, nipple can slowly become flat and finally disappear. 6. Nipple overflow: Breast cancer accounts for a larger proportion of nipple overflow with lumps. The overflow can be colorless, milky white, yellowish, brown, bloody, etc.; it can be watery, blood-like, plasma-like or purulent; the amount of overflow can be more or less, and the interval is not consistent.