When coughing and spitting yellow sputum, it is necessary to go to the hospital for routine blood tests, sputum culture, and chest X-ray and CT examinations, etc. The treatment includes antibiotic anti-inflammatory, expectorant, and comprehensive treatment, as follows: 1. Antibiotic anti-inflammatory treatment: such patients mostly have lower respiratory tract bacterial infections, such as acute bronchitis or mild pneumonia patients, and can take oral antibiotics to reduce inflammation, often using cefaclor, cefdinir, levofloxacin, amoxicillin, etc. 2. 2. Expectorant treatment: Patients with more sputum can take oral expectorant drugs, such as tranylcypromine tablets, acetylcysteine effervescent tablets, etc. 3. Comprehensive treatment: Patients with more serious lung infections, such as pneumonia, lung abscess, bronchial dilatation, etc., also need to be treated with intravenous anti-inflammatory drip sensitive antibiotics, with the necessary expectorant nebulized inhalation and other symptomatic treatment. The course of anti-infective treatment must be sufficient at this time. In conclusion, patients with cough with yellow sputum must be treated early with the appropriate anti-infective symptomatic treatment.