Purpura is mainly characterized by bleeding or petechiae on the skin and mucous membranes, while leukemia is usually accompanied by fever, anemia and pain in addition to bleeding or petechiae. 1. Leukemia (1) Fever: Leukemia patients are usually accompanied by infection, causing fever or even high fever. (2) Anemia: Leukemia patients may be accompanied by anemia, even severe anemia. (3) Pain: Acute leukemia is often accompanied by pain symptoms such as arthralgia, bone pain, headache, etc. There may also be localized pressure pain in the lower part of the sternum. (2) Purpura: In addition to skin ecchymosis, purpura may be accompanied by abdominal pain, vomiting and other symptoms. The onset of purpura is usually due to contact with allergic drugs or foods, or viral infections. Once you find ecchymosis on the skin, you should go to a regular hospital in time to find out the cause, make a clear diagnosis under the guidance of the doctor, and carry out treatment.