Anyone who has a normal sexual life after marriage without contraception and has not conceived after two years of cohabitation is said to be infertile. In recent years, the age of marriage and childbirth among young people in China has generally been delayed, and the adverse effects of many factors such as environmental pollution, social factors and sexually transmitted diseases have significantly increased the number of infertility patients. In the World Health Organization’s Standard Examination and Diagnosis Manual for Infertile Couples (1995), the diagnosis of infertility has been set at one year, and has gradually been recognized by the medical profession. Infertility is one of the common diseases in obstetrics and gynecology. According to the International Women’s Federation in 1990, about 8% of couples of childbearing age have infertility problems. The World Health Organization predicts that infertility will become the third most common disease after tumors and cardiovascular diseases. Although infertility is not a fatal disease, it can cause personal suffering, couple relationship break-up, family discord and other social problems is a major medical and social problem worldwide and should be given sufficient attention. I. Emotional manifestations of infertility The basic emotional manifestation of infertility is the typical reaction of loss and mourning. The traditional concept that it is natural and natural to have children after marriage still exists deeply in our society. Therefore, when a couple is infertile for many years after marriage, people around them will be concerned to inquire or enthusiastically provide advice or even secret recipes, which will increase the pressure of infertile couples. 1, the emotional impact of infertility: the psychological problem brought by long-term infertility is a kind of emotional stress, which can stimulate the overproduction of adrenocortical hormones and lead to excessive androgens and affect ovulation. Violent emotional ups and downs can excite the sympathetic nerves and release catecholamines, which can cause tubal spasms as well as hinder the growth of follicles in the ovaries and the secretion of luteinizing hormone. 2. Crisis of infertility: The most serious emotional disorder of infertile couples is the feeling of loss of control. This feeling of being out of control extends to other aspects of life, making the couple feel depreciated in self-esteem and self-confidence, and having to endure uncertainty about the cause of infertility, ambiguity in the physician’s attitude, wavering life goals, uncertainty about the effectiveness and safety of treatment, etc. during the consultation process. The sexual dysfunction caused by the pressure to the couple blocks the expression of emotions between the couple and causes tension between the couple. Second, how to provide psychological care and support for infertile couples? As health care professionals, in addition to somatic treatment for infertility patients, they should pay more attention to their psychological treatment, listen to their feelings and treat them with a gentle attitude to make patients feel secure and trustful. 1.Establish a good doctor-patient relationship with the patient, and win the patient’s trust with a warm, considerate, sympathetic and sincere attitude, i.e., take the initiative to communicate with the patient leading to the patient’s initiative to talk in order to assess the patient’s existing problems. 2, do a good job of diversion, create a relaxed and easy to accept the consultation environment, according to different conditions, different mentality, carefully do a good job of psychological diversion, while creating a relaxed and easy to accept the consultation environment, do not disclose the patient’s infertility, eliminate the patient’s sensitivity and inferiority complex. 3. Encourage couples to visit the doctor at the same time, the husband accompanying the wife can increase the woman’s sense of tranquility and comfort, the two sides cooperate, and also improve the cure rate, at the same time, the husband receives health education and establishes the correct concept of pregnancy and childbirth, which can also play a role in promoting the consolidation of marriage. 4.Take effective health education. Some patients, especially senior intellectuals, although they know some scientific knowledge about infertility, they mostly know it half-heartedly, due to the one-sided belief that infertility cannot be cured, thus increasing the psychological pressure. It is important to promote the health knowledge of pregnancy and childbirth in layman’s language, answer the questions raised by patients, guide them to actively cooperate with treatment, and educate them to treat the problem of pregnancy and childbirth correctly. In addition, physicians should pay attention to improving their own qualities. Patients expect physicians to be kind, compassionate, amiable, good at communication, knowledgeable, competent and technically skilled, and skilled in their work, and should have some specific knowledge of infertility and psychological counseling skills to assist in diagnosing and treating patients’ specific problems. With the continuous progress of medical science, people have a deeper and deeper understanding of infertility and have made great progress in the treatment of infertility, and the influence of psychological factors on infertility has been recognized as an infertility factor. This shows that psychological treatment has become an important aspect of infertility treatment and that appropriate psychological care is essential to reduce the mental stress of infertile couples and to make them cooperate with their physicians to obtain the best possible outcome. The prevalence of depression in women with infertility in the study was 25% and anxiety was 26%. In the normal population, 5% had anxiety changes and 5% to 10% had depression, which shows that the level of anxiety and depression in women with infertility is significantly higher than in the normal population, indicating a correlation between the psychological state of anxiety and depression and infertility. Increasing clinical attention is being paid to the influence of psychological factors on infertility, and anxiety and depression are common responses to psychological stress. Clinical studies have found that excessive depression or anxiety can affect fertility through the hypothalamic-pituitary-gonadal axis, mainly affecting the triggering of gonadotropin release by dopamine and norepinephrine, leading to menopause, tubal spasms, changes in cervical mucus and other sexual dysfunctions in women resulting in infertility. Psychotherapy is in a sense sometimes more important than drug therapy, which requires physicians to understand the patient’s psychological state and family and social situation, and to take appropriate care initiatives to relieve and alleviate the patient’s mental pain and improve the drug efficacy of the disease as well as the patient’s quality of life in response to the patient’s psychological characteristics.