A child is a sweet burden for the parents, but the Creator occasionally makes mistakes, and some problematic child, a deformed child, can come into the world and become a painful burden to the family, the family and the society, and an endless torture to the child itself. Therefore, every parent should not forget their responsibility while they are immersed in the joy of pregnancy, even if they are reluctant, they should go to the hospital, do the maternity checkups, listen to the doctor’s advice to supplement the baby’s essential substances, do prenatal eugenics screening, and meet the genetic counselor if necessary. Because genetics is the basis of eugenics, in nature, only seeds with good innate qualities can bear good fruit. By the same token, only a healthy fetus that has inherited good genes from both parents is likely to be eugenic. You must seek pre-conception genetic counseling from your doctor if: one of the spouses has a congenital disease; both spouses have a family history of genetic diseases; you have delivered a baby with a genetic disease or congenital disease; you are married to a close relative; the woman is over 35 years old; you have had three or more consecutive miscarriages, etc. Those who have a history of exposure to teratogenic factors before or during pregnancy and need genetic counseling during pregnancy include: perinatal medication; pregnancy after alcoholism; viral infection; vaccination; radiation exposure; failure of medication for contraception; poor psychological factors; those who need medication or surgery for other diseases during pregnancy, or those who need radiotherapy or chemotherapy for malignant tumors. Eugenics starts from the pre-conception preparation. When women are preparing for pregnancy, they should avoid contact with harmful substances such as newly renovated houses, newly bought cars, radioactive substances, take folic acid tablets from 3 months before pregnancy to prevent fetal neural tube malformation, and check whether they are infected with toxoplasma, rubella virus, cytomegalovirus and herpes simplex virus. If the infection is acute, it is best not to get pregnant at this time. After pregnancy, you should have regular prenatal checkups, taking weight and blood pressure at each checkup, checking for edema, reviewing the fetal position, listening to the fetal heartbeat, and performing ultrasound and fetal heart monitoring if necessary. The current living conditions of people allow us to perform prenatal screening for every pregnant woman. Prenatal screening usually refers to maternal serum prenatal screening. Prenatal screening is performed on all non-high-risk pregnant women from 9-13+6 weeks and 15-20 weeks of gestation to screen the risk value of pregnant women carrying trisomy 21 (congenitally stupid child), trisomy 18, open neural tube abnormalities and other chromosomal abnormalities, and to perform prenatal diagnosis on high-risk pregnant women to try to avoid the birth of these types of fetuses. Some people may say that in the past, people did not do any tests, but still had good children? I say this maybe you can understand: the general environment of people’s survival is deteriorating, the small environment of men and women who want to give birth is also deteriorating, human fertility is not getting stronger, but only downhill, coupled with the selfless implementation of family planning policies, we can still do what we want to have a baby, and what kind of birth I also support? Nowadays, there are more and more pregnant women in big cities who marry later and have more children later, and as the age of pregnant women increases, the rate of fetal chromosomal aberrations increases, and the birth rate of children with Down’s syndrome also increases with age. 0.3% of pregnant women with Down’s syndrome are born at the age of 30, 0.6% at the age of 35, and up to 1.6% after the age of 40, so prenatal diagnosis (also known as intrauterine diagnosis, pre-birth diagnosis) needs to be carried out for older primiparous women. Therefore, prenatal diagnosis (also known as intrauterine diagnosis, prenatal diagnosis) is required for primiparous women of advanced age to rule out Down’s syndrome as the most common chromosomal disorder. Prenatal diagnosis is required for high-risk pregnant women who are ≥35 years old; have had a child with a chromosomal disorder; have a history of unexplained spontaneous abortion, malformation, stillbirth or neonatal death; have a fetus suspected of having a chromosomal abnormality by prenatal ultrasound; or have a couple with a chromosomal genetic abnormality. Prenatal diagnosis includes: ① Early prenatal diagnosis by chorionic villus cells (check karyotype, micronucleus, etc.), at about 11 weeks, a biopsy needle is used to enter the uterine cavity through the cervix or abdominal wall to reach the placental position, and a small amount of chorionic tissue is removed for examination. ② Amniocentesis for amniotic fluid and amniotic fluid cells (16-20 weeks of gestation). Under the guidance of ultrasound, amniotic fluid and embryonic shed cells are collected by needle puncture and examined. These are very accurate methods to detect fetal abnormalities and this method is relatively safe. ③Cordocentesis , after 20 weeks, fetal cord blood is taken through the abdomen with a special needle and examined. This method can detect whether there are chromosomal abnormalities and hereditary blood disorders. The chance of causing miscarriage is higher than that of amniotic fluid examination. The above examination methods are only used for high-risk pregnant women, and need to be examined in hospitals with certified qualifications, and need to be performed by qualified doctors who have a strict grasp of the indications and contraindications for the procedure. ④ B-mode ultrasonography, each scan is short, painless if the pregnant woman, harmless to the fetus, with the possibility of detecting body surface abnormalities and anomalies, usually needs to be done 3-4 times, at 12 and 24 weeks and 32 weeks respectively. This test can be used to further determine the date of pregnancy and any developmental abnormalities, such as cleft palate, organ abnormalities, and also to detect multiple births, and should be done by all pregnant women. Fetoscopy, now used sparingly. China is one of the countries with a high incidence of birth defects, with 800,000-1.2 million children born with defects every year, and on average, one defective child is born every 30 seconds. We hope that through our efforts to reduce the birth of defective children in Shaoguan and surrounding areas, may every parent have a healthy and smart child, and a happy family with a father, a mother and a healthy child.