1, prevention of colds: mother in early pregnancy to avoid colds, such as attention to insulation, less public places, especially less shopping in large commercial buildings. 2, early examination: 2 months of pregnancy, do ultrasound if the child’s heart has a heart malformation and more complex, such as left ventricular dysplasia syndrome and other congenital heart disease for which there is no good treatment, the mother should consider shedding the fetus. 3, the influence of radiation: some people believe that the child congenital heart disease and ultrasound, surrounding radioactive substances, etc. have a relationship, however, these statements have not been conclusively proven. 4.Environmental pollution: some special smell and irritation felt after renovation (such as irritation to the cornea: astringent and dry eyes; irritation to the respiratory tract: itchy throat, dry cough, etc.) are caused by toxic gases (such as formaldehyde, etc.), which may affect the development of the fetus. 5, parental influence: parents drinking alcohol, smoking and taking drugs can affect the development of the fetus.