Many people’s understanding of rheumatic diseases, most stay in the elderly back and leg pain, rheumatoid arthritis. In fact, rheumatic immune diseases are a large group of common diseases, facial limb rash, muscle and joint pain, anemia and swelling and other symptoms, at first glance should go to dermatology, orthopedics, hematology, etc., in fact, may be rheumatic immune diseases caused by the trouble. Rheumatic immune diseases can invade any tissue in the body. In case of damage to two or more systems or organs, always remember to consider visiting a rheumatologist to buy valuable treatment time. Normal immune function lies in the ability to fight against invaders such as bacteria and viruses or foreign substances such as organs that have received transplants, and also in the removal of its own mutated cancer cells, aging and necrotic cells, etc. Autoimmune diseases occur when immune function is disrupted and mistakenly uses its own tissues as invaders. Some autoimmune diseases are highly targeted, damaging only one tissue or organ. For example, damage to insulin-producing pancreatic islet cells leads to type I diabetes; damage to the thyroid gland causes Hashimoto’s thyroiditis or hyperthyroidism. In contrast, rheumatic diseases with immune dysfunction are not well targeted and lead to damage to multiple sites, such as systemic lupus erythematosus, systemic vasculitis, polymyositis/dermatomyositis, etc. In cases such as swelling and pain of various joints and muscles, damage to two or more organs, such as nephritis + arthritis, rash + nephritis, arthralgia + pleural effusion, anemia + nephritis, or recurrent fever for more than one month and the diagnosis is still unclear and anti-infection treatment is ineffective, it is necessary to promptly seek a rheumatologist to clarify the presence of rheumatic disease to avoid misdiagnosis. She introduced that many clinical specialties of difficult and complicated diseases, may be very common rheumatism. The rheumatism is not the patent of the elderly, many rheumatic diseases onset age is young and strong period. For example, systemic lupus erythematosus is a typical autoimmune disease, which occurs in young women, with a peak incidence of 15 to 40 years old, and can develop rapidly or slowly, with a variety of clinical manifestations. There is also ankylosing spondylitis, a joint disease that affects young people, especially young men. Early manifestations of ankylosing spondylitis are mainly pain in the neck, back, lumbar, sacral, and shoulder spines, or pain or swelling in the large joints of the lower extremities or heels, often misdiagnosed as sprains or strain injuries. Eosinophilic fasciitis is more common in men, with a male to female ratio of 2:1. The age of onset is 30 to 60 years old, and there is often a history of overexertion before onset. Strenuous exercise, trauma, cold and upper respiratory tract infection may also trigger the disease. The disease often starts with swelling, tautness and hardness of the skin of the limbs, or with erythema of the skin and limitation of joint movement. Patients often have deep subcutaneous tissue swelling, and when the affected limb is lifted up, the surface skin is depressed. Generally no obvious systemic symptoms, a few patients with joint muscle pain, weakness, low fever, etc., may also lead to limb contracture and functional impairment over time. After Ms. Zhang was diagnosed, she underwent active treatment with hormones, cyclophosphamide and other drugs, and now the symptoms of muscle stiffness and tendon contracture of the limbs have improved and her condition is effectively controlled. Ten symptoms to consider seeing rheumatology Rheumatic diseases include many specific diseases, there are ten major categories, nearly 100 types of disease. Common ones such as rheumatoid arthritis, systemic lupus erythematosus, systemic vasculitis, polymyositis/dermatomyositis, systemic sclerosis, ankylosing spondylitis, dry syndrome, osteoarthritis, gout, etc. However, there are similarities in the aura manifestations of rheumatic diseases. 1, joint swelling or pain, if there is obvious swelling of the joints, hurry to seek medical attention. 2. Myalgia and muscle weakness. 3. Both hands or feet turn white when cold or mood changes, and turn red or purple when warm or mood stabilizes. 4. Dryness of the mouth and eyes, recurrent swelling of the parotid glands. 5. Lower back pain and alternating hip pain, heel pain or pain at other tendon end areas. 6. Swelling and proteinuria. 7. Anemia, thrombocytopenia. 8. Unexplained prolonged fever. 9. Recurrent ophthalmia, skin rash, skin breakdown. 10. Unexplained arteriovenous thrombosis.