Lower extremity intravascular thrombosis is a common clinical disease, mainly secondary to heart disease, diabetes, vasculitis, post-surgery, prolonged bed rest and long-term standing. Its incidence has been on the rise in recent years, and the corresponding treatment methods have been improved with the advancement of modern technology, thus ensuring the best possible efficacy of thrombotic disease treatment at the time of injury to patients. Transcatheter thrombolysis is a direct, safe, aggressive, and effective interventional treatment method. At present, it has been widely used in clinical practice. Its mechanism of action is to insert the venous catheter tip into the thrombus through percutaneous puncture and use a high-dose shock or micro-pump to continuously push urokinase to maintain a high drug concentration in the venous thrombus, so that the thrombus will be rapidly dissolved, which can better preserve the deep venous valves in the proximal part of the affected limbs and reduce the occurrence of deep venous valve insufficiency in the lower limbs, and secondly, it can Secondly, it can promote the dissolution of as many thrombi as possible to open more collateral branches, improve venous reflux, reduce venous pressure, relieve swelling and edema symptoms, and help restore muscle pump function. At present, comprehensive clinical treatment such as early diagnosis of thrombosis, selection of appropriate minimally invasive means, active use of thrombolytic therapy, insistence on oral administration of sodium florin tablets and drugs to improve microcirculation after discharge, and active coordination with treatment of underlying diseases are the main measures for active treatment and prevention of restenosis.