The main causes of muscle twitching pain in the lower back are many diseases, which need to be judged in conjunction with the patient’s past history and accompanying symptoms. The main clinical conditions are lumbar muscle strain, trauma, lumbar disc herniation, hypocalcemia, lumbar back muscle fasciitis, etc. 1, lumbar muscle strain: long-term physical activity, lifting heavy objects, ambulatory work, sedentary, etc., overload the lumbar region, which can lead to chronic injury inflammation of the lumbar muscles and their attachment points fascia, periosteum, etc., resulting in symptoms of lumbar muscle twitching pain; 2, trauma: when external forces lead to Acute lumbar sprain, if the sprain is not handled properly and treated in a timely manner, it will lead to chronic inflammatory injury to the lumbar muscles and fascia, manifesting as lumbar muscle twitch-like pain and lumbar muscle spasm, etc.; 3, lumbar intervertebral disc herniation: this disease is mainly caused by intervertebral disc degeneration, fibrous ring rupture, nucleus pulposus protrusion stimulation or compression of nerve roots and cauda equina nerve, etc. At the onset, patients can feel lumbar muscle twitch-like pain 4, hypocalcemia: due to hypoparathyroidism, vitamin D deficiency, etc., can affect the absorption of calcium, resulting in a decrease in the level of serum calcium ions in the body, so the patient will have lumbar muscle twitching pain, may also be accompanied by abnormal sensation, weakness and other symptoms; 5, lumbar back myofasciitis: mostly due to long-term lumbar back muscle strain, cold and other stimuli, thus induce aseptic inflammation of the lumbar back fascia, which can lead to diffuse soreness and pain in the lumbar back, and when the disease attacks, the symptoms of muscle twitching pain can occur; 6, other diseases: such as tumors, tuberculosis, infection in the lumbar area, when the lesion invades and compresses the nerve vessels, it can cause muscle twitching pain in the lumbar area.