Why should leukocyte-raising injections be used with caution in cancer chemotherapy?

       Chemotherapy as a treatment for cancer has unavoidable side effects, the most common of which are hematopoietic suppression and liver and kidney toxicity. White blood cell and platelet reduction is very common, and serious reduction is even life-threatening.  In clinical practice, some doctors repeatedly treat patients with chemotherapy, the result of which is to cause severe suppression of the patient’s bone marrow and severe reduction of white blood cells. The patient is very happy to see that the white blood cells will be raised rapidly after the injection, not knowing that there are great risks involved: 1. The white blood cells from the leukostasis injection are immature and infantile cells, which are poor combatants. Therefore, the use of leukostatic injection is to “pull up the seedlings to help grow”, the white blood cells are often high and low, completely different from the normal situation.  2. Repeated use of leukapheresis and chemotherapy will accelerate the depletion of bone marrow hematopoietic function, leading to long-term low white blood cell platelet count and even life-threatening. Even if the patient successfully passes chemotherapy, he or she may become anemic for a long time as a result, and the survival period will be affected.  3. Boosting injection is a colony-stimulating factor, which may stimulate the growth of tumor cells while stimulating the growth of hematopoietic cells, and even lead to the early recurrence of tumor, making the efficacy of chemotherapy greatly reduced.  Under what circumstances is leukostimulation injection necessary? When the bone marrow function is severely suppressed (degree IV) and life-saving white-growing injections are needed. However, this situation is not allowed to recur.  What about mild leukopenia? It is best to combine the treatment with Chinese medicine at the same time, which is both more effective and less toxic to chemotherapy. If you must use the white blood cell boosting injection, it should be moderate, and the white blood cells should be raised to about 10,000, to avoid sudden highs and lows.  What should I do if my white blood cells are always decreasing and I want to complete multiple chemotherapy treatments? We can reduce the chemotherapy dose appropriately with TCM treatment. (There is no need to worry that the reduction of chemotherapy drugs will affect the efficacy, because for most cancers, the efficacy of chemotherapy is already poor. The increase in toxicity is more obvious than the increase in efficacy when the dose of chemotherapy is increased).