Long-term insomnia will cause disorders in the regulation of the body’s plant nerves, causing endocrine disorders in the body, resulting in a decline in immunity, leading to a series of problems in the body, the main problems are as follows: 1, endocrine disorders: it will lead to an increase in the body androgen, oil secretion, resulting in acne, pigmentation, etc., and also easily lead to obesity; 2, disorders of the plant nerves: causing patients to experience memory loss, dizziness, chest tightness, panic abdominal pain, diarrhea, vomiting, female patients are prone to menstrual disorders, male patients are prone to seminal emission, impotence and other symptoms; 3, reduce immunity: patients’ immunity becomes poor, prone to colds or other infectious diseases; 4, neurological damage: long-term insomnia reduces brain circulation, brain ischemia, hypoxia will lead to brain nerve damage, patients can not concentrate, poor mental state, appear drowsy, 5, aggravate the underlying disease: their own hypertension patients blood pressure is not easy to control, in addition to easily induce coronary angina attack; 6, endanger mental health: long-term insomnia will lead to poor mental state of patients, easy to appear tension, fear, anxiety, depression and other bad mental state. Patients are advised to control sleep time, listen to soothing music before bed, drink some warm milk, or do aerobic exercise to promote sleep. If insomnia is still not relieved, patients can seek medical attention and take appropriate sedative and sleeping drugs, but not for a long time to avoid drug dependence.