Whether protein in the urine can be cured by itself is related to the cause of proteinuria, generally proteinuria caused by physiological factors can be cured by itself, while pathological factors such as those caused by various glomerulonephritis and pyelonephritis can’t be cured by itself. 1. Physiological proteinuria: including locomotor proteinuria and postural proteinuria. Symptoms can disappear after rest and can be cured by themselves. 2. Pathologic proteinuria: proteinuria is diagnosed by 24-hour urine protein quantification greater than 150mg. Common causes include glomerulonephritis such as membranous nephropathy, IgA nephropathy, hypertensive nephropathy, diabetic nephropathy and so on. General treatment includes controlling blood pressure, blood sugar, blood lipids, diuresis and treatment for the original disease. It is recommended that patients with protein in urine should go to the hospital in time to improve the relevant examinations under the guidance of the doctor, and if it is caused by pathological factors, it should be actively treated to avoid the development of the disease.