Cerebral amyloid angiopathy (CAA) is a cerebrovascular disease caused by Aβ amyloid deposition. There is growing evidence that CAA is extremely common in the elderly population and is an important cause of spontaneous lobar hemorrhage and age-related cognitive decline. It is often associated with Alzheimer’s disease.
Different pathologic changes in cerebrovascular amyloidosis can lead to a variety of clinical manifestations, and it has also been proposed that about half of the patients aged 80 years and older have no obvious clinical symptoms, so its diagnosis is based on imaging and clinical.
Imaging shows multiple cerebral microinfarcts and microhemorrhages, lobar hemorrhages, and iron deposition on the cortical surface, etc. Clinical manifestations tend to be of acute/subacute onset, mainly cognitive and behavioral changes, headache, local neurological deficits, and epileptiform seizures.
The diagnosis of vascular amyloidosis should be based on the doctor’s diagnosis and treatment plan to improve the relevant examinations and follow the doctor’s instructions for comprehensive treatment.