Walker is the trade name for vonorasan fumarate, which works to inhibit gastric acid production and gastrointestinal mucosal damage in the treatment of reflux esophagitis. Vonorasan fumarate is a kind of western medicine, from a pharmacological point of view, because it contains the ingredient of vonorasan fumarate, vonorasan reversibly inhibits the activity of H⁺-K⁺-ATPase in a competitive manner of potassium ions, which can stay in the cellular site of the stomach wall for a long time and inhibit the production of gastric acid, so vonorasan fumarate in the clinic can be used to treat reflux esophagitis. If patients are allergic to this product, they need to avoid taking it, and for patients who are being treated with atazanavir or rilpivirine, they also need to avoid taking vonorasan fumarate. Secondly, some patients may experience adverse reactions such as diarrhea, abdominal pain, nausea, and bloating during the administration of the drug. To summarize, when the patient’s body is not feeling well, they should go to the hospital in time to consult the doctor, and take vonorasan fumarate under the doctor’s guidance, do not use the drug on their own, so as not to delay the condition and adversely affect their health.