Mosquito bites with red spots can be applied according to the symptoms of skin lesions with topical drugs, systemic medication, as follows: 1. Topical drugs: mosquito bites can be localized topical glucocorticoid cream, including dexamethasone, mometasone furoate, halometasone and other drugs, which can effectively play an anti-inflammatory, anti-allergic effect, alleviate the redness, swelling, itching and pain after being bitten by mosquitoes. 2. Systemic medication: patients with obvious itching take antihistamine drugs, such as benadryl, loratadine, ebastine and other drugs to improve itching symptoms. If the lesions are generalized and the allergic reaction is severe, short-term oral glucocorticosteroids, such as prednisone, methylprednisolone, etc.. After being bitten by mosquitoes and red spots, please do not self-medicate to avoid aggravation of skin lesions. It is recommended to go to the hospital and follow the doctor’s instructions to apply the relevant drugs.