The symptoms of duodenal ulcer mainly include epigastric pain, abdominal distension, anorexia, acid reflux, belching, vomiting blood and black stools. 1. Epigastric pain: pain in the nature of hunger-like discomfort, vague pain, dull pain, distension, burning pain, etc., mostly in the 2~3 hours after the meal, lasting until the next meal or take antacids completely relieved. Nocturnal pain may occur, manifested as waking up with pain during sleep. Most patients have recurrent episodes, alternating between episodes and periods of relief. 2. Dyspeptic symptoms: some patients may also manifest epigastric distension, anorexia, acid reflux, belching and so on. 3. Gastrointestinal bleeding: duodenal ulcer patients with duodenal mucosa damage, bleeding or even erosion, manifested as vomiting blood and black stool. When the above symptoms occur, patients should go to the hospital in time, under the guidance of the doctor to clarify the diagnosis and standardize the treatment.