Triglyceride 3.95mmol/L belongs to the state of elevated, may be related to diet, lifestyle habits, etc., but also may be related to diabetes, nephrotic syndrome, pancreatitis and other diseases, whether it is serious or not depends on the patient’s specific situation, can not be generalized. Triglycerides are energy substances in the body that supply and store energy. Normal serum triglyceride content is 0.45~1.69mmol/L, fasting 1.70~2.25mmol/L is borderline elevated, ≥2.26mmol/L is elevated state, so triglyceride 3.95mmol/L is significantly elevated. However, triglyceride will be affected by the daily diet, lifestyle habits of large fluctuations, such as eating high cholesterol foods such as animal offal before the examination, alcohol abuse before the examination, stay up late before the examination, and so on. This is usually a physiological increase and is not serious, but it is important to change lifestyle and dietary habits to avoid triggering the disease. In addition, elevated triglycerides may be caused by familial hypertriglyceridemia, diabetes mellitus, hypothyroidism, nephrotic syndrome, pancreatitis, atherosclerosis, glycogen storage disease, etc. Whether it is serious or not depends on the patient’s specific condition, and it is not possible to rely on the value of triglycerides alone. It is recommended that patients consult a doctor in time to make appropriate life adjustments or treatment.